SimpliGraft Multi-layered More Complete Barrier Protection

AMNION LAYER VERSATILE BARRIER
PROTECTION

SimpliGraft®, a dehydrated amnion allograft, provides a protective barrier and supports an optimal environment for healing a wide range of acute and chronic wounds.1,2 Ready-to-use with no required orientation, it offers flexibility for your practice and product application.1

Product SimpliGraft

AN AMNION ALLOGRAFT

As an amnion-only allograft, SimpliGraft® is thin and flexible1,3

SimpliGraft Layers3

SimpliGraft Layers

Native Placental Tissue Layers4

Native Placental Tissue Layers

AMNIOTIC TISSUES SUPPORT HEALING

SimpliGraft® provides a protective barrier and extracellular matrix (ECM) scaffold to support the body’s ability to repair underlying damaged tissue, such as acute and chronic wounds1,2,4

SimpliGraft is processed to retain native components of the amnion layer3

ECM Proteins

ECM Scaffold

Growth Factors and Cytokines

Growth Factors & Cytokines

VERSATILITY FOR A WIDE RANGE OF WOUNDS

SimpliGraft® may be used to support healing in a wide range of partial- and full-thickness acute and chronic wounds1

Wide range of wounds

Convenient and sterilized

  • Ready-to-use, ambient temperature storage (2°C to 30°C)
  • No required orientation–either side of the product may be applied to the wound bed
  • Terminally sterilized with a sterility assurance level (SAL) of 10-6
SimpliGraft Amnion Allograft
PRODUCT NUMBERPRODUCT DESCRIPTIONTOTAL SIZE (CM2)BILLABLE UNITSHCPCS CODEGTIN
586-001SimpliGraft
2x3cm		66Q434000849777013680
585-002SimpliGraft
4x4cm		1616Q434000849777013697
585-003SimpliGraft
4x8cm		3232Q434000849777013703
585-004SimpliGraft
8x10cm		8080Q434000849777010696
585-005SimpliGraft
7x15cm		105105Q434000849777010702

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Please refer to the SimpliGraft instructions for use for usage and safety information.

References:

  1. SimpliGraft Allograft Tissue Information and Instructions for Use. Canton, MA: Organogenesis Inc; 2025.
  2. Brantley JN, Verla TD. Adv Wound Care. 2015;4(9):545-559.
  3. Data on File. SimpliGraft. Organogenesis, Inc.
  4. Niknejad H, et al. Eur Cells Mater. 2008;15:88-99.