FortaPerm® Tissue Integration

FortaPerm^®

Stress urinary incontinence is the leakage of urine as a result of increased pressure (i.e. coughing, laughing, sneezing) upon the bladder. This is a result of the bladder neck dropping to a position where it does not squeeze shut when pressure is applied. FortaPerm^® is used as a sling to raise the bladder neck back into a position where it is able to squeeze shut when pressure is applied.

For tissue support, FortaPerm^® adds long-term structural support to soft tissue where native tissue is either insufficient or absent.

The FortaPerm^® product is a multi-layer construct with a high level of collagen crosslinking. Due to the unique design attributes, FortaPerm^® resists remodeling and degradation, provides long-term bio-mechanical strength and incorporates as a distinct tissue layer. It is designed for surgical applications that require long-term support (e.g., stress urinary incontinence sling, vaginal prolapse repair).

Studies demonstrate that FortaPerm^® constructs with a high level of collagen crosslinking:

• Resist degradation and remain intact long-term
• Are well-integrated at the suture line
• Do no elicit a foreign body response
• Are as strong as adjacent host tissue at 360 days