Bioactive Wound Healing

Apligraf® is a living cell-based product, developed by Organogenesis and indicated for the treatment of venous leg ulcers and diabetic foot ulcers.

Apligraf® is:

  • the first bio-engineered cell based product to receive FDA approval (in 1998).
  • the only commercially available bi-layered bio-engineered cell based product.
  • the only product approved by the FDA to treat both diabetic foot ulcers and venous leg ulcers

The two layers of Apligraf® make it effective in speeding up wound healing and achieving healing in wounds previously unresponsive to treatment.

For more information on Apligraf® please visit www.apligraf.com.

For Apligraf regulatory documentation, please visit